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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Surgery. 2023 Jun 3;174(2):259–267. doi: 10.1016/j.surg.2023.04.016

Table 3.

Modelled effect sizes from restricted cubic splines (RCS) analyses, depicting adjusted association between BMI and perioperative outcomes. Reference BMI is set as 25kg/m2.

BMI Operative time Blood loss Pringle maneuver Blood transfusion Open conversion Morbidity Major morbidity Length of stay 90-day mortality
(kg/m2) MD (95% CI) MD (95% CI) RR (95% CI) RR (95% CI) RR (95% CI) RR (95% CI) RR (95% CI) MD (95% CI) RR (95% CI)
15 −43 (−71 to −15) −26 (−168 to 116) 0.94 (0.78 to 1.14) 1.53 (1.03 to 2.25) 0.58 (0.25 to 1.31) 0.88 (0.64 to 1.2) 1.57 (0.96 to 2.57) 0.2 (−0.5 to 0.8) 3.72 (1.7 to 8.12)
16 −38 (−61 to −14) −22 (−142 to 99) 0.96 (0.82 to 1.12) 1.44 (1.03 to 2.01) 0.61 (0.3 to 1.23) 0.89 (0.68 to 1.17) 1.47 (0.97 to 2.24) 0.2 (−0.4 to 0.8) 3.21 (1.61 to 6.41)
17 −32 (−52 to −13) −18 (−117 to 82) 0.97 (0.85 to 1.11) 1.36 (1.03 to 1.8) 0.65 (0.36 to 1.15) 0.9 (0.71 to 1.15) 1.38 (0.98 to 1.97) 0.2 (−0.2 to 0.7) 2.77 (1.52 to 5.06)
18 −27 (−43 to −12) −14 (−93 to 66) 0.99 (0.89 to 1.09) 1.29 (1.02 to 1.62) 0.69 (0.44 to 1.08) 0.91 (0.74 to 1.12) 1.3 (0.98 to 1.73) 0.3 (−0.1 to 0.7) 2.39 (1.44 to 3.99)
19 −22 (−34 to −10) −10 (−71 to 52) 1 (0.92 to 1.08) 1.22 (1.01 to 1.46) 0.73 (0.52 to 1.02) 0.92 (0.78 to 1.09) 1.22 (0.98 to 1.53) 0.3 (0 to 0.6) 2.07 (1.36 to 3.15)
20 −17 (−26 to −8) −6 (−53 to 42) 1.01 (0.95 to 1.08) 1.15 (0.99 to 1.34) 0.77 (0.61 to 0.98) 0.93 (0.82 to 1.07) 1.15 (0.96 to 1.38) 0.3 (0.1 to 0.6) 1.79 (1.28 to 2.49)
21 −12 (−20 to −5) −2 (−41 to 37) 1.02 (0.98 to 1.08) 1.09 (0.95 to 1.25) 0.82 (0.69 to 0.97) 0.95 (0.86 to 1.04) 1.09 (0.93 to 1.28) 0.4 (0.2 to 0.5) 1.54 (1.2 to 1.98)
22 −8 (−15 to −1) 0 (−35 to 36) 1.03 (0.99 to 1.08) 1.05 (0.93 to 1.18) 0.86 (0.75 to 1) 0.96 (0.9 to 1.02) 1.04 (0.9 to 1.21) 0.3 (0.2 to 0.5) 1.35 (1.13 to 1.6)
23 −5 (−10 to 1) 1 (−28 to 31) 1.03 (0.99 to 1.07) 1.02 (0.92 to 1.12) 0.91 (0.81 to 1.03) 0.97 (0.93 to 1.01) 1.01 (0.9 to 1.14) 0.3 (0.1 to 0.4) 1.19 (1.07 to 1.33)
24 −2 (−5 to 1) 1 (−16 to 17) 1.02 (0.99 to 1.04) 1 (0.95 to 1.06) 0.95 (0.89 to 1.02) 0.98 (0.97 to 1) 1 (0.93 to 1.07) 0.2 (0.1 to 0.2) 1.08 (1.02 to 1.14)
25 Ref Ref Ref Ref Ref Ref Ref Ref Ref
26 2 (−1 to 5) 1 (−14 to 16) 0.99 (0.97 to 1.01) 1 (0.95 to 1.05) 1.05 (0.98 to 1.12) 1.02 (1 to 1.03) 1.01 (0.95 to 1.07) −0.2 (−0.2 to −0.1) 0.96 (0.89 to 1.02)
27 4 (−1 to 9) 5 (−20 to 30) 0.98 (0.95 to 1.01) 0.99 (0.91 to 1.08) 1.09 (0.98 to 1.22) 1.04 (1.01 to 1.06) 1.03 (0.93 to 1.14) −0.3 (−0.4 to −0.2) 0.93 (0.8 to 1.09)
28 6 (0 to 12) 11 (−20 to 42) 0.98 (0.94 to 1.02) 0.98 (0.88 to 1.09) 1.14 (1 to 1.32) 1.06 (1.01 to 1.1) 1.05 (0.92 to 1.19) −0.4 (−0.5 to −0.2) 0.93 (0.72 to 1.19)
29 8 (1 to 15) 19 (−15 to 54) 0.99 (0.94 to 1.03) 0.97 (0.86 to 1.09) 1.2 (1.03 to 1.4) 1.08 (1.02 to 1.14) 1.07 (0.93 to 1.24) −0.5 (−0.6 to −0.3) 0.93 (0.65 to 1.34)
30 10 (3 to 18) 29 (−9 to 68) 0.99 (0.95 to 1.04) 0.95 (0.83 to 1.09) 1.25 (1.06 to 1.48) 1.1 (1.02 to 1.19) 1.1 (0.94 to 1.29) −0.5 (−0.7 to −0.3) 0.94 (0.58 to 1.52)
31 12 (4 to 21) 41 (−4 to 85) 1.01 (0.95 to 1.06) 0.94 (0.79 to 1.1) 1.31 (1.1 to 1.56) 1.12 (1.02 to 1.23) 1.13 (0.95 to 1.35) −0.6 (−0.8 to −0.4) 0.96 (0.52 to 1.74)
32 15 (4 to 25) 53 (0 to 105) 1.02 (0.96 to 1.08) 0.92 (0.75 to 1.12) 1.37 (1.14 to 1.65) 1.14 (1.02 to 1.28) 1.17 (0.96 to 1.42) −0.6 (−0.9 to −0.4) 0.97 (0.47 to 1.99)
33 17 (5 to 29) 65 (2 to 128) 1.03 (0.96 to 1.11) 0.9 (0.71 to 1.14) 1.43 (1.16 to 1.76) 1.17 (1.02 to 1.34) 1.21 (0.96 to 1.52) −0.7 (−1 to −0.4) 0.98 (0.42 to 2.28)
34 19 (5 to 34) 77 (3 to 151) 1.05 (0.97 to 1.14) 0.88 (0.66 to 1.17) 1.5 (1.19 to 1.9) 1.19 (1.02 to 1.39) 1.24 (0.95 to 1.62) −0.7 (−1.1 to −0.4) 1 (0.38 to 2.61)
35 22 (5 to 38) 89 (3 to 176) 1.06 (0.97 to 1.17) 0.87 (0.62 to 1.2) 1.57 (1.2 to 2.05) 1.21 (1.01 to 1.45) 1.28 (0.94 to 1.74) −0.8 (−1.2 to −0.4) 1.01 (0.34 to 2.99)
36 24 (5 to 43) 102 (2 to 201) 1.08 (0.97 to 1.2) 0.85 (0.58 to 1.24) 1.64 (1.21 to 2.22) 1.24 (1.01 to 1.51) 1.32 (0.93 to 1.88) −0.8 (−1.3 to −0.4) 1.03 (0.31 to 3.42)
37 26 (4 to 48) 114 (2 to 227) 1.09 (0.97 to 1.24) 0.83 (0.54 to 1.28) 1.72 (1.23 to 2.41) 1.26 (1.01 to 1.58) 1.36 (0.92 to 2.02) −0.9 (−1.4 to −0.3) 1.04 (0.28 to 3.92)
38 28 (4 to 53) 126 (1 to 252) 1.11 (0.97 to 1.28) 0.82 (0.51 to 1.32) 1.8 (1.23 to 2.61) 1.29 (1.01 to 1.64) 1.4 (0.9 to 2.18) −0.9 (−1.5 to −0.3) 1.06 (0.25 to 4.49)
39 31 (4 to 58) 139 (−1 to 278) 1.13 (0.96 to 1.31) 0.8 (0.47 to 1.36) 1.88 (1.24 to 2.84) 1.31 (1.01 to 1.71) 1.45 (0.89 to 2.36) −1 (−1.6 to −0.3) 1.07 (0.22 to 5.14)
40 33 (3 to 63) 151 (−2 to 304) 1.14 (0.96 to 1.35) 0.78 (0.44 to 1.4) 1.97 (1.25 to 3.1) 1.34 (1.01 to 1.78) 1.49 (0.87 to 2.55) −1 (−1.7 to −0.3) 1.09 (0.2 to 5.89)