Skip to main content
. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: J Inherit Metab Dis. 2022 Dec 11;46(2):335–347. doi: 10.1002/jimd.12577

Figure 4. Livers of Sumf1S153P/S153P and Sumf1A277V/A277V mice.

Figure 4.

Representative CD68 (A) and LAMP1 (B) immunofluorescence and EM (C) of livers from 24–week-old Sumf1S153P/S153P (S153P/S153P) and Sumf1A277V/A277V (A227V/A227V) mice compared to Sumf1+/+ (+/+) controls. LAMP1 immunofluorescence, magnification: 20x, scale bar: 20 μm. CD68 immunofluorescence, magnification: 10x scale bar: 50 μm. In C, the back arrows point to lysosomal-like structures; scale bar: 500 nm. (D) Quantifications of lysosomal number and size on EM are shown as mean ± SEM. ****p<0.0001. One-way ANOVA followed by Tukey’s post hoc test.