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. 2023 Dec 22;79(2):211–240. doi: 10.1093/jac/dkad372

Table 1.

Characteristics of in vitro studies

Study Total no. of isolates Mycobacterium species Growth Isolate origin Phenotypic assay Genotypic assay Gene investigated
Aguilar-Ayala et al. (2017)6 18 M. abscessus, M. chelonae, M. cosmeticum, M. duvalii, M. flavescens, M. fortuitum, M. franklinii, M. mageritense, M. mucogenicum, M. neoaurum, M. parafortuitum, M. peregrinum, M. phlei, M. smegmatis, M. wolinskyi Rapid CCUG strains and UCL strain MBC MIC Luria broth, REMA Sanger sequencing atpE
Alexander et al. (2017)62 25 M. intracellulare Slow Clinical MIC CAMHB WGS and targeted atpE and mmT5
Andries et al. (2005)24 26 M. abscessus, M. avium, M. fortuitum, M. kansasii, M. marinum, M. smegmatis, M. ulcerans Rapid and slow Non-clinical MIC MBC 7H11, Mueller–Hinton plates WGS atpE
Asami et al. (2021)25 70 M. abscessus Rapid Clinical MIC CAMHB N/A N/A
Brown-Elliott et al. (2017)8 104 MAC and M. avium Slow Clinical and reference MIC CAMHB N/A N/A
Cantillon et al. (2022)26 2 M. chimaera, M. abscessus Rapid and slow Reference MIC REMA N/A N/A
Chew et al. (2021)27 211 M. abscessus Rapid Clinical MIC Sensititre plate N/A N/A
Chew et al. (2021)28 32 M. fortuitum Rapid Clinical MIC Sensititre plate N/A N/A
Dupont et al. (2017)29 38 M. abscessus Rapid Clinical and non-clinical MIC CAMHB Sanger sequencing atpE
Gumbo et al. (2020)30 20 M. abscessus Rapid Clinical and reference MIC CAMHB Sequencing N/A
Gutiérrez et al. (2019)31 6 M. abscessus Rapid Non-clinical and reference MIC 7H10 N/A N/A
Huitric et al. (2007)32 50 M. avium, M. intracellulare, M. chelonae, M. fortuitum, M. mageritense, M. phlei, M. vaccae, M. kansasii, M. malmoense, M. gordonae, M. simiae, M. scrofulaceum, M. hiberniae, M. interjectum, M. szulgai, M. terrae, M. conspicuum, M. novocastrense, M. xenopi, M. shimoidei Rapid and slow Clinical MIC 7H10 Sanger sequencing atpE
Kim et al. (2017)33 2 M. abscessus Rapid Non-clinical and reference MIC REMA N/A N/A
Kim et al. (2019)54 307 M. abscessus, M. avium, M. intracellulare, M. kansasii Rapid and slow Clinical MIC CAMHB N/A N/A
Li et al. (2018)34 197 M. abscessus Rapid Clinical MIC CAMHB WGS atpE, MAB_4384
Lin et al. (2022)35 111 M. avium, M. intracellulare, M. marseillense, M. colombiense, M. yongonense, M. vulneris, M. arosiense Slow Clinical MIC Sensititre plate N/A N/A
Litvinov et al. (2021)36 166 M. avium, M. intracellulare Slow Clinical MIC 7H9 N/A N/A
Lounis et al. (2008)37 1 M. smegmatis Rapid Reference MIC 7H11, 7H11 + 5% BSA; LJ N/A N/A
Maeda et al. (2021)38 1 M. smegmatis Rapid Non-clinical MIC R liquid medium WGS atpE, rpoB, prpE
Martin et al. (2019)39 17 M. avium, M. chimaera, M. intracellulare, M. kansasii, M. simiae, M. xenopi Slow Clinical MIC REMA, 7H10 Sanger sequencing atpE
Pang et al. (2016)40 685 M. abscessus, M. avium, M. fortuitum, M. intracellulare, M. kansasii Rapid and slow Clinical MIC CAMHB Sanger sequencing atpE
Ransom et al. (2022)41 1 M. grossiae Rapid Clinical MIC Not reported WGS N/A
Richard et al. (2018)43 3 M. abscessus Rapid Non-clinical and reference MIC CAMHB N/A N/A
Richard et al. (2018)42 7 M. abscessus Rapid Non-clinical and reference MIC CAMHB WGS MAB_2299c
Richter et al. (2018)44 1 M. abscessus Rapid Non-clinical and reference MIC CAMHB N/A N/A
Ruth et al. (2019)45 28 M. abscessus, M. avium, M. chimaera, M. fortuitum, M. intracellulare, M. kansasii, M. malmoense, M. simiae, M. xenopi Rapid and slow Clinical and reference MBC MIC 7H10, CAMHB N/A N/A
Sarathy et al. (2020)61 12 M. abscessus Rapid Clinical and reference MIC 7H9, CAMHB N/A N/A
Schulthess et al. (2022)46 62 M. abscessus Rapid Clinical and reference MIC CAMHB N/A N/A
Segala et al. (2012)47 37 M. abscessus, M. fortuitum, M. smegmatis Rapid Clinical, non-clinical and reference MIC 7H11 Sequencing atpE
Sorayah et al. (2019)48 17 M. abscessus Rapid Clinical MIC 7H9 N/A N/A
Srivastava et al. (2022)49 21 M. kansasii Slow Clinical and reference MIC 7H9 N/A N/A
Vesenbeckh et al. (2017)50 20 M. avium, M. intracellulare Slow Clinical MIC 7H10 N/A N/A
Vesenbeckh et al. (2017)51 20 M. abscessus Rapid Clinical MIC 7H10 N/A N/A
Yu et al. (2019)52 260 M. avium, M. intracellulare, M. kansasii, M. arupense, M. xenopi, M. szulgai, M. fuerth, M. parascrofulaceum, M. terrae, M. malmoense, M. abscessus, M. fortuitum, M. gordonae, M. chelonae, M. holsaticum, M. massiliense, M. asiaticum, M. celatum, M. chimaera, M. gastri, M. microti, M. nonchromogenicum, M. rhodesiae, M. scrofulaceum, M. triviale, M. agri, M. aichiense, M. aurum, M. austroafricanum, M. chitae, M. chubuense, M. cosmeticum, M. diernhoferi, M. fallax, M. farcinogenes, M. flavescens, M. gadium, M. gilvum, M. goodii, M. mucogenicum, M. neoaurum, M. obuense, M. parafortuitum, M. peregrinum, M. phlei, M. porcinum, M. pulveris, M. senegalense, M. septicum, M. simiae, M. sphagni, M. smegmatis, M. thermoresistibile, M. tokaiense, M. vaccae Rapid and slow Clinical and reference MIC CAMHB N/A N/A
Zhu et al. (2022)53 182 M. kansasii, M. avium, M. intracellulare, M. abscessus, M. abscessus subsp. massiliense, M. agri, M. aichiense, M. aurum, M. austroafricanum, M. brumae, M. confluentis, M. chelonae, M. chitae, M. chubuense, M. cosmeticum, M. diernhoferi, M. fortuitum, M. fortuitum subsp. fortuitum, M. mucogenicum, M. neworleansense, M. obuense, M. parafortuitum, M. peregrinum, M. pulveris, M. senegalense, M. septicum, M. smegmatis, M. thermoresistibile, M. tokaiense, M. asiaticum, M. arosiense, M. celatum, M. chimaera, M. gastri, M. gadium, M. gordonae, M. interjectum, M. kubicae, M. marinum, M. microti, M. nonchromogenicum, M. parascrofulaceum, M. rhodesiae, M. scrofulaceum, M. szulgai, M. sphagni, M. shimoidei, M. terrae, M. triviale, M. xenopi, M. tuberculosis (H37Rv) Rapid and slow Clinical MIC CAMHB N/A N/A
Zweijpfenning et al. (2019)68 3 M. avium Slow Clinical MIC CAMHB WGS atpE; MAV_2512

LJ, Löwenstein-Jensen; N/A, not applicable.