Table 6.
In animal model studies | In human studies | ||
---|---|---|---|
Regimen | Mycobacterium species | Regimen | Species |
RIF or RFP and/or Q203 or CLF | M. ulcerans | BDQ + LVX | M. fortuitum |
CLR and/or AMK | M. avium | BDQ + OMC or CLF | M. abscessus |
BDQ combined with either IPM or CLF | M. abscessus | BDQ + MFX | M. marinum |
BDQ + TDZ and CLF | M. avium |
RIF, rifampicin; AMK, amikacin; BDQ, bedaquiline; CLF, clofazimine; CLR, clarithromycin; IPM, imipenem; RFP, rifapentine; Q203, telacebec; MFX, moxifloxacin; OMC, omadacycline; TDZ, tedizolid; LVX, levofloxacin.