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. 2023 Dec 9;79(2):262–270. doi: 10.1093/jac/dkad368

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© The Author(s) 2023. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — PTA plots for 0.5 h infusion of 4.5 g piperacillin/tazobactam q8h under steady-state conditions. (a) PTA of piperacillin for 50% fT_>MIC, (b) PTA of tazobactam for 50% fT_>Ct, (c) PTA of piperacillin for 100% fT_>MIC and (d) PTA of tazobactam for 100% fT_>Ct. Comparison between concentrations before albumin supplementation (grey lines) and after albumin supplementation (red lines) with simulated (n = 500) piperacillin/tazobactam concentrations. Horizontal lines denote breakpoints of 90% PTA. This figure appears in colour in the online version of JAC and in black and white in the print version of JAC.