Table 1.
The association between patients’ characteristics and HBV-induced cirrhosis risk
| Variables | Total (%) | Cirrhosis (%) | Univariate | Multivariatea | ||
|---|---|---|---|---|---|---|
| (n = 1754) | (n = 59) | HR (95%CI) | P-value | HR (95% CI) | P-value | |
| Age (years old) | ||||||
| <37 | 909 (51.82) | 18 (30.51) | 1.00 | 1.00 | ||
| ≥37 | 845 (49.28) | 41 (69.49) | 2.49 (1.43–4.33) | 1.34 × 10-3 | 1.97 (1.11–3.51) | 0.021 |
| Gender | ||||||
| Female | 355 (20.24) | 6 (10.17) | 1.00 | 1.00 | ||
| Male | 1399 (79.76) | 53 (89.83) | 2.26 (0.97–5.27) | 0.058 | 1.74 (0.71–4.27) | 0.224 |
| Smoking status | ||||||
| Never smokers | 1239 (70.64) | 30 (50.85) | 1.00 | 1.00 | ||
| Ever smokers | 515 (29.36) | 29 (49.15) | 2.33 (1.39–3.91) | 1.27 × 10-3 | 1.69 (0.96–2.98) | 0.070 |
| Drinking status | ||||||
| Never drinkers | 918 (52.34) | 23 (38.98) | 1.00 | 1.00 | ||
| Ever drinkers | 836 (47.66) | 36 (61.02) | 1.69 (1.00–2.86) | 0.051 | 1.24 (0.71–2.6) | 0.443 |
| ALBI Grade | ||||||
| 1 | 617 (35.18) | 14 (23.73) | 1.00 | 1.00 | ||
| 2 and 3 | 1137 (64.82) | 45 (76.27) | 1.88 (1.03–3.43) | 0.040 | 1. 56 (0.84–2.89) | 0.160 |
| Receiving antiviral treatment | ||||||
| Yes | 1456 (83.01) | 42 (71.19) | 1.00 | 1.00 | ||
| No | 298 (16.99) | 17 (28.81) | 1.83 (1.04–3.22) | 0.037 | 1.82 (1.03–3.22) | 0.039 |
a
Adjusted for age, gender, smoking and drinking status, ALBI grade, antiviral treatment.