TABLE 1.

Antimicrobial activity of a semipurified acetic acid extract of human terminal ileal mucosa^a

Bacterium	% Antimicrobial activity (mean ± SD)
S. typhimurium CS015	94.9 ± 5.1
S. typhimurium ATCC 14028 (wild type)	8.6 ± 8.7
E. coli ATCC 25922	93.7 ± 2.8
E. coli ATCC 29648	97.1 ± 0.6
S. faecalis ATCC 19433	78.5 ± 21.5
S. faecium ATCC 19433	95.6 ± 1.6
S. aureus ATCC 9144	92.5 ± 6.3
Beta-hemolytic Streptococcus group G	30.4 ± 0.7

^aThe mucosal extract was applied to a cation-exchange column, and an eluted fraction (designated fraction 15) was tested for antimicrobial activity with the 96-well microtiter plate assay. Antimicrobial activity is expressed as percent reduction in bacterial growth compared to bacterial growth in the control (0.1% acetic acid only) after incubation at 37°C for 5 h.