Table 3.
Anthropometric values, laboratory findings, and Medscore among NAFLD patients and healthy controls at baseline (T0) and at the end of the study (T12): means (SD) and ΔT0–T12 as means (SD) in the differences of the values at T0 and at T12.
| NAFLD patients (58) | Healthy controls (73) | |||||||
|---|---|---|---|---|---|---|---|---|
| T0 | T12 | ΔT0–T12 | P ∗ | T0 | T12 | ΔT0–T12 | P ∗ | |
| BMI (kg/m2) | 31.4 (5.5) | 30.5 (5.6) | 0.9 (1.2)§ | <0.001 | 24.0 (3.8) | 24.0 (3.8) | 0.0 (0.9)§ | 0.97 |
| Waist circumference (cm) | 105 (14) | 104 (13) | 0.9 (4.7)# | 0.16 | 87 (11) | 88 (11) | −0.8 (3.8)# | 0.04 |
| Total cholesterol (mg/dL) | 207 (34) | 211 (35) | −3.6 (28) | 0.29 | 196 (40) | 200 (35) | −4.4 (24) | 0.13 |
| HDL | 50 (12) | 53 (14) | −3.2 (7.5) | <0.01 | 66 (18) | 66 (17) | −0.4 (8.1) | 0.43 |
| LDL | 128 (31) | 132 (29) | −3.7 (23) | 0.22 | 114 (38) | 117 (34) | −3.1 (22) | 0.17 |
| Triglycerides (mg/dL) | 152 (96) | 128 (58) | 24 (76) | 0.06 | 82 (39) | 86 (43) | −4.1 (31) | 0.60 |
| Glycemia (mg/dL) | 98 (19) | 99 (20) | −0.5 (14) | 0.57 | 85 (9) | 85 (10) | 0.2 | 0.47 |
| Insulinemia (μU/mL) | 16 (15) | 13 (9) | 2.4 (11) | 0.12 | 5 (4) | 5 (4) | −0.1 | 0.94 |
| AST (U/L) | 22 (10) | 22 (8) | 0.2 | 0.71 | 19 (7) | 21 (8) | −1.4 (7) | 0.05 |
| ALT (U/L) | 41 (21) | 40 (21) | 1.6 (21) | 0.43 | 29 (19) | 30 (19) | −0.7 (15) | 0.35 |
| HOMA-IR index | 3.9 (4.5) | 3.6 (3.2) | 0.3 (4.2) | 0.23 | 1.1 (0.9) | 1.1 (0.9) | 0.0 | 0.86 |
| Medscore | 12 (3) | 16 (3) | −3.2 (3.1)§ | <0.001 | 15 (4) | 15 (4) | −0.2§ | 0.20 |
§ P < 0.001 and #P < 0.01 for the comparison between the differences among NAFLD patients and healthy controls (according to Wilcoxon nonparametric test for paired data). ∗Mann–Whitney test.