. 2023 Dec 14;102(1):e207815. doi: 10.1212/WNL.0000000000207815

Table 2.

Clinical and Polysomnographic Data in NT1 and Non-NT1 Subjects

Variable	Non-NT1 (n = 88)		NT1 (n = 112)		p Value
Clinical data	%	n	%	n	p Value
Male sex	60.2	53	56.3	63	0.572^a
HLA-DQB1*0602	12.3		94.5		<0.001^a
Cataplexy	0	0	98.2	108	<0.001^a
Sleep paralyses	13.9	11	30.0	33	0.010^a
Hallucinations	10.1	8	46.4	51	<0.001^a
Disturbed nocturnal sleep	15.4	12	47.7	51	<0.001^a
	Mean	SD	Mean	SD
Age	12.6	4.0	11.8	3.4	0.052^b
CSF hcrt-1 (pg/mL)	342.6	47.2	30.0	53.9	<0.001^b
Disease onset age	11.0	4.5	9.2	3.0	<0.001^b
Disease duration	2.0	2.9	2.5	2.9	0.681^b
aESS	10.9	5.2	14.6	3.4	0.002^b
BMI Z-score	0.5	1.1	1.2	1.0	<0.001^b
Neurophysiological data
N-PSG	Mean	SD	Mean	SD
n-SL (min)	15.2	16.5	5.5	7.3	<0.001^b
n-REML (min)	81.6	35.2	26.1	48.0	<0.001^b
n-TST (min)	466.5	86.8	471.5	75.0	0.863^b
n-TIB (min)	505.2	90.9	528.7	76.5	0.349^b
SE (%)	92.3	7.7	89.7	7.7	0.013^b
N1% (% of TST)	6.1	4.6	10.7	4.7	<0.001^b
N2% (% of TST)	41.0	10.6	39.5	8.3	0.055^b
N3% (% of TST)	29.2	10.3	26.1	9.2	0.358^b
REM% (% of TST)	23.4	5.1	23.5	5.7	0.937^b
MSLT
MSLT SL (min)	14.8	4.1	3.6	2.9	<0.001^b
SOREMP (n)	0.35	0.82	4.25	0.99	<0.001^b
D-PSG
dn-NAP (n)	1.20	1.08	2.81	1.82	<0.001^b
d-TST (min)	84.0	79.6	137.2	73.2	0.001^b
d-SOREMPs (n)	0.17	0.48	2.00	1.48	<0.001^b

Abbreviations: aESS = adapted Epworth Sleepiness Scale; BMI = body mass index; CSF hcrt-1 = CSF hypocretin-1; d = daytime; dn-NAP = number of daytime naps; D-PSG = daytime polysomnography; MSLT = multiple sleep latency test; n = nocturnal; N1, N2, N3 = non-REM sleep stage 1, 2, 3; non-NT1 = non-narcolepsy type 1; NT1 = narcolepsy type 1; REML = REM sleep latency; SE = sleep efficiency; SL = sleep latency; SOREMP = sleep-onset REM period; TIB = time in bed; TST = total sleep time.

χ² test.

Mann-Whitney test.