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Baseline scans were considered the MRI scans acquired ≤6 months from the beginning of clinical follow-up. 3D-EPI = 3-dimensional echo planar imaging; BPF = brain parenchymal fraction; CSA = cross-sectional area; PIRA = progression independent of relapse activity; PMS = progressive multiple sclerosis; RRMS = relapsing-remitting multiple sclerosis.
