Table 2.
Higher Detection Frequency in Neuronal Cells
| Protein Name | Abbreviation | Accession # | Functional Category |
| Alkaline Phosphatase | PPBT | Q29486 | Membrane Phosphatase |
| Aminopeptidase N | AMPN | P79171 | Membrane Enzyme |
| Arylsulfatase B precursor | ARSB | P33727 | Lysosomal Enzyme |
| Brain-derived neurotrophic factor precursor | BDNF* | Q9TST3 | Neurotrophic Factor |
| Cellular tumor suppressor p53 | P53* | P41685 | Nuclear |
| Dipeptidyl peptidase IV | DPP4 | Q9N2I7 | Membrane Enzyme |
| Glutamate decarboxylase, 67 kDa isoform | DCEI | P14748 | Cytoplasmic Enzyme |
| Integrin beta-1 precursor | ITB1 | P53713 | Membrane Receptor |
| Interleukin-1 beta convertase precursor | ICE1 | Q9MZV6 | Cytoplasmic Enzyme |
| Lysosomal alpha-mannosidase precursor | M2B1 | O46432 | Lysosomal Enzyme |
| Major prion protein precursor | PRIO | O18754 | Membrane Prion Protein |
| Mast/stem cell growth factor receptor precursor | KIT | Q28889 | Membrane Tyrosine Kinase Receptor |
| NADH-Ubiquinone oxidoreductase chain 5 | NU5M | P48921 | Mitochondrial Enzyme |
| Polycomb complex protein BMI-1 | BMI1 | Q9TST0 | Nuclear Protein |
| Pyruvate kinase, M1 isozyme | KPYM | P11979 | Pyruvate Kinase |
| Serum albumin precursor*** | ALBU* | P49064 | Cytoplasmic Albumin Protein |
| Sodium/calcium exchanger 1 precursor | NAC1 | P48767 | Membrane Calcium Ion Channel (Plasma Membrane) |
| T-cell surface glycoprotein CD8 beta chain precursor | CD8B | P79336 | Membrane Receptor |
| Toll-like receptor 4 precursor | TLR4 | P58727 | Membrane Receptor |
| Transferrin receptor protein 1 | TFR1 | Q9MYZ3 | Membrane Receptor |
| Zona pellucida sperm-binding protein 2 precursor | ZP2* | P47984 | Membrane Receptor |
| Zona pellucida sperm-binding protein B precursor | ZP4 | P48834 | Membrane Receptor |
Proteins with higher frequency of detection in complex forms in neuronal cells compared to melanoma. Ten proteins were detected in single as well as in complex forms in both melanoma and neuronal cells. These proteins displayed a higher frequency of detection in neuronal cells than in melanoma. Four proteins Fel d 2 /ALBU*, BDNF*, tumor suppressor protein (P53*) and zona pellucida-2 (ZP2*) were detected both in single (*) and complex forms only in neuronal cells. These proteins were present only in complexes in melanoma cells. The ALBU and P53* proteins also showed increased frequency of detection in the neuronal cells than in melanoma (also see Fig 2C*) and BDNF and ZP2 showed similar detection frequencies in the two cell types.