Table 1.
Demographic, clinical and neuropsychological characteristics of patients
| nfvPPA (n = 104) | |||
|---|---|---|---|
| Mean ± SD | Range | Missing | |
| Demographic | |||
| Age at scan | 68.55 ± 7.12 | 51–82 | 0 |
| Sex (male/female) | 33/71 | N/A | 0 |
| Handedness (right/left/ambidextrous) | 91/11/2 | N/A | 0 |
| Years of education | 16.13 ± 2.88 | 12–28 | 0 |
| Clinical | |||
| Estimated age at first symptom onset | 64.07 ± 7.18 | 44–79 | 1 |
| Estimated years since first symptom onset | 4.39 ± 1.93 | 1–10 | 1 |
| MMSE (30) | 25.24 ± 4.47 | 12–30 | 6 |
| CDR (3) | 0.41 ± 0.40 | 0–2 | 6 |
| Visuospatial function | |||
| Benson figure copy (17) | 14.47 ± 2.10 | 4–17 | 10 |
| VOSP number location (10) | 8.67 ± 1.56 | 3–10 | 16 |
| Visual memory | |||
| Benson figure 10 min free recall (17) | 10.30 ± 3.25 | 0–16 | 10 |
| Verbal memory | |||
| CVLT-MS trials 1–4 (36) | 22.54 ± 6.64 | 9–35 | 14 |
| CVLT-MS 30 s free recall (9) | 6.21 ± 2.31 | 0–9 | 14 |
| CVLT-MS 10 min free recall (9) | 5.82 ± 2.49 | 0–9 | 14 |
| CVLT-MS recognition (9) | 8.19 ± 1.10 | 4–9 | 14 |
| Executive function/working memory | |||
| Backward digit span (8) | 3.49± 1.43 | 0–8 | 10 |
| Modified trails (lines per minute) | 17.83 ± 29.08 | 0–270 | 13 |
| Stroop colour naming (1 min) | 41.98 ± 15.55 | 6–79 | 39 |
| Stroop interference (1 min) | 25.09 ± 11.10 | 1–49 | 35 |
| Design fluency (1 min) | 6.10 ± 2.82 | 0–13 | 12 |
| Letter fluency (D words in 1 min) | 5.90 ± 4.11 | 0–23 | 11 |
| Category fluency (animals in 1 min) | 11.05 ± 6.41 | 0–33 | 10 |
| Language production | |||
| WAB speech fluency rating (10) | 6.19 ± 2.62 | 0–10 | 11 |
| Boston naming test (15) | 12.39 ± 2.95 | 0–15 | 6 |
| WAB repetition (100) | 85.34 ± 15.66 | 15–100 | 15 |
| MSE AoS severity rating (7) | 2.68 ± 1.86 | 0–7 | 1 |
| MSE dysarthria severity rating (7) | 2.09 ± 2.07 | 0–7 | 1 |
| Language comprehension | |||
| Pyramids and palm trees test–pictures (% correct) | 94.25 ± 7.77 | 56–100 | 28 |
| Peabody picture vocabulary test (16) | 14.31 ± 1.96 | 7–16 | 14 |
| Sentence comprehension (% correct) | 88.35 ± 13.27 | 36–100 | 16 |
The numbers in parentheses indicate the maximum possible score (or rating). AoS = apraxia of speech; CDR = Clinical Dementia Rating; CVLT = California Verbal Learning Test; MMSE = Mini-Mental State Examination; MSE = Motor Speech Evaluation; nfvPPA = non-fluent/agrammatic variant of primary progressive aphasia; SD = standard deviation; VOSP = Visual Object and Space Perception Battery; WAB = Western Aphasia Battery.