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. 2023 Sep 6;147(2):427–443. doi: 10.1093/brain/awad298

Figure 2.

Figure 2

Interaction between α-synuclein preformed fibrils and MerTK. Induced pluripotent stem cell-derived microglia (iMGL) were incubated with α-synuclein (α-syn) preformed fibrils (PFFs) or vehicle on ice for 30 min and a proximity ligation assay (PLA) was performed. (A) Representative flow cytometry plots. (B) Quantification of the PLA signals. A repeated measure one-way ANOVA was performed followed by Sidak’s post hoc test. Mean ± SEM of n = 3; **P < 0.01.