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Shape factor index (SFI) overview. (A) SFI is a dimensionless descriptor of shape, as shown with the same myofiber in three different sizes. (B) High SFI values indicate increased deviation from a circle, as illustrated by two fibres with similar cross‐sectional area but different shapes. (C) SFI values for a circle and four myofibers of different shapes. The area and perimeter values are from actual measurements of myofibers on cryosections.
