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. 2024 Feb 1;15:972. doi: 10.1038/s41467-024-45216-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Mononuclear cells isolated from peripheral blood collected before treatment (C1D1) and at 5 weeks (C2D8) were analyzed by flow cytometry. Patients were categorized based on their CTCAE grade of immune-mediated toxicity into Grade 1–2 (mild) (n = 5), Grade 3–5 (severe) (n = 24), and no immune-mediated toxicity (none) (n = 19). Results are expressed as mean + SEM, one-sided paired t test. Gating started is shown in supplementary Fig. 1A. One representative dot plot from each time point is shown. Source data are provided as a Source Data file.