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. 2024 Feb 1;15:972. doi: 10.1038/s41467-024-45216-z

Fig. 5. The association between chemokine serum levels and patient clinical outcome.

Fig. 5

Plasma samples from 34 patients at baseline prior to treatment (C1D1) and at 5 weeks (C2D8) were analyzed for presence chemokines by Luminex (Panel HCYP3MAG-63K-08 for CXCL9 and CXCL10, Millipore). A Heatmap generated from non-transformed data separate for each chemokine. Units are in pg/mL; one-sided paired t test. B–D Gardner-Altman plot with denotes log-transformed (B) CXCL9 (n = 34), (C) CXCL10 (n = 34), and (D) CXCL11 (n = 34) values at C1D1 and C2D8 collection timepoints. One-sided paired t test. Increased group is created based on >15% change, and decreased group is based on <15% change. The 15% cutoff was determined arbitrarily by testing significance in 15% increments of 15%, 30%, and 45%, respectively. Source data are provided as a Source Data file.