Table 2.
Predictive values of UA (per 10 µmol/L) for adverse outcomes.
| Univariable Cox regression model | Multivariable Cox regression | Multivariable Cox regression | ||||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | |||||
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| All-cause mortality | 1.077 (1.045–1.109) | < 0.001 | 1.106 (1.060–1.153) | < 0.001 | 1.143 (1.069–1.221) | < 0.001 |
| Cardiac death | 1.081 (1.043–1.120) | < 0.001 | 1.090 (1.042–1.140) | < 0.001 | 1.168 (1.064–1.282) | 0.001 |
| HF hospitalization | 1.054 (1.024–1.084) | < 0.001 | 1.062 (1.025–1.099) | 0.001 | 1.093 (1.035–1.155) | 0.001 |
Model 1, adjustment for age, sex and BMI.
Model 2, adjustment for Model 1 plus hypertension, DM, CHD, AF, SBP, BNP, FPG, TC, TG, eGFR, and the use of ACEI/ARB/ARNI, β-blocker, diuretics and antisterone.
UA uric acid, HF heart failure, HR hazard ratio, BMI body mass index, DM diabetes mellitus, CHD coronary heart disease, AF atrial fibrillation, SBP systolic blood pressure, BNP B-type natriuretic peptide, FPG fasting plasma glucose, TC total cholesterol, TG total triglyceride, eGFR estimated glomerular filtration rate, ACEI angiotensin- converting enzyme inhibitor, ARB angiotensin receptor blocker, ARNI angiotensin receptor neprilysin inhibitor.