Table 3.
Predictive values of NLR for adverse outcomes.
| Univariable Cox regression model | Multivariable Cox regression | Multivariable Cox regression | ||||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | |||||
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| All-cause mortality | 1.164 (1.095–1.237) | < 0.001 | 1.172 (1.088–1.262) | < 0.001 | 1.238 (1.096–1.398) | 0.001 |
| Cardiac death | 1.171 (1.090–1.258) | < 0.001 | 1.174 (1.075–1.281) | < 0.001 | 1.286 (1.105–1.497) | 0.001 |
| HF hospitalization | 1.111 (1.047–1.179) | 0.001 | 1.122 (1.048–1.201) | 0.001 | 1.163 (1.055–1.282) | 0.002 |
Model 1, adjustment for age, sex and BMI.
Model 2, adjustment for Model 1 plus hypertension, DM, CHD, AF, SBP, UA, BNP, FPG, TC, TG, eGFR, and the use of ACEI/ARB/ARNI, β-blocker, diuretics and antisterone.
NLR neutrophil-to-lymphocyte ratio, HF heart failure, HR hazard ratio, BMI body mass index, DM diabetes mellitus, CHD coronary heart disease, AF atrial fibrillation, SBP systolic blood pressure, UA uric acid, BNP B-type natriuretic peptide, FPG fasting plasma glucose, TC total cholesterol, TG total triglyceride, eGFR estimated glomerular filtration rate, ACEI angiotensin- converting enzyme inhibitor, ARB angiotensin receptor blocker, ARNI angiotensin receptor neprilysin inhibitor.