Fig. 2.

Knocking out (KO) the effects of NEDD4L on ischemic stroke injury. A. TTC staining was used to detect the ischemic area of NEDD4L-KO or WT mice after MCAO treatment, n = 6. B. Neurological function scores of mice in each treatment group, n = 6. C. Brain water content of mice in each treatment group, n = 6. D. QRT-PCR was used to detect the mRNA expression levels of NEDD4L after OGD/R or NEDD4L treatment, n = 3. E. CCK-8 was used to detect the cell viability after OGD/R or NEDD4L treatment, n = 3. F. The Edu staining was used to detect the cell viability after OGD/R or NEDD4L treatment, n = 3. G. The TUNEL staining was used to detect the cell apoptosis after OGD/R or NEDD4L treatment, n = 3