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The methods for obtaining SGSCs/SGPCs. SGSCs/SGPCs are able to be obtained by adherent culture or suspension culture (generating salisphere). In addition, PSCs derived from somatic reprogramming can be differentiated into SGSCs/SGPCs. PSCs, pluripotent stem cells; SGPCs, salivary gland progenitor cells; SGSCs, salivary gland stem cells.
