Fig. 2.
Dietary GOS enriches specific lactobacilli and alleviates Salmonella infection in mice. (A) Experimental scheme. (B) Body weight changes. (C) Fecal titers of Salmonella on d 19. The colon length (D), histological score (E), tight junction protein expression (F), and cytokine mRNA expression (G) in the colonic segments on d 19 were shown. (H) Relative abundances of different dominant lactobacilli on d 19. CON, mice treated with PBS; S. Tm, Salmonella-infected mice; GOS, mice fed GOS and infected with Salmonella. OCLN, occludin; CLDN-1, claudin-1; ZO-1, zonula occludin-1; TNF-α, tumor necrosis factor-α; IFN-γ, interferon-γ; IL-1β, interleukin-1β; IL-6, interleukin-6. * P<0.05, ** P<0.01, *** P<0.001.