Table 1.
Combined indexes for studies reporting the association of frailty and mortality by different frailty tools
Effect size | Combined | Heterogeneity | Egger’s test | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Index | 95%CI | Z statistic | P value | I 2 (%) a | Chi square | P value | Bias (95%CI) | P value | ||
HR for mortality | Total | 2.66 | 1.96 -3.63 | 6.21 | <0.001 | 67.8 | 21.75 | 0.003 | 3.43 (0.79 -4.74) | 0.014 |
LFI | 2.63 | 1.75 -3.97 | 4.62 | <0.001 | 78.2 | 18.34 | 0.001 | 3.57 (-0.31 - 7.46) | 0.061 | |
CFS | 2.75 | 1.30 – 5.78 | 2.66 | 0.008 | - | - | - | - | - | |
FFI | 2.81 | 1.45-5.47 | 3.05 | 0.002 | 47.0 | 1.89 | 0.169 | - | - | |
Another effect size and other definition | OR | 3.73 | 1.90 – 7.31 | 3.85 | <0.001 | 0 | 0.05 | 0.827 | - | - |
HR (continues definition of FFI) | 1.37 | 1.23 -1.52 | 4.14 | <0.001 | 0 | 0.09 | 0.766 | - | - |
Abbreviations: CFS, Clinical Frailty Score; FFI, Fried Frailty Index; HR, Hazard ratio; LFI, Liver Frailty Index; OR, Odds ratio