TABLE 2.
Group | Rabbit serum | Anti-tD15 antibody titer | No. bacteremic/9 challenged | Mean CFU/25 μl of blood | Pb |
---|---|---|---|---|---|
1 | Anti-Hia | 6,400 | 0 | 0 | 0.00004 |
2 | Anti-tD15 | 51,200 | 0 | 0 | 0.00004 |
3 | Preimmune | <200 | 9 | 190 |
Five-day-old infant rats (nine per group) were passively immunized s.c. with 0.1 ml of indicated rabbit antiserum or preimmune serum. Twenty hours later, the animals were challenged i.p. with freshly grown Hia strain ATCC 9006 (105 CFU, 0.1 ml) as described in Materials and Methods.
Statistical significance of the difference in results obtained between antisera and preimmune sera, established by the Fisher exact test.