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. Author manuscript; available in PMC: 2024 Feb 2.
Published in final edited form as: Aliment Pharmacol Ther. 2021 Oct 9;54(11-12):1416–1431. doi: 10.1111/apt.16630

Table 3.

The association of functional dyspepsia, rumination syndrome and the overlap group of both with the examined risk factors in a multivariate regression model.

Risk factor Group
Functional dyspepsia Overlap Rumination syndrome
Demographic and exposure risk factors
Female gender 2.04 (1.33–3.10) 3.22 (1.19–8.47) 1.79 (1.21–2.63)
Smoking - - 1.89 (1.28–2.78)
Diet risk factors
Gluten free diet (current or previous) - - 1.58 (1.14–2.19)
Non-coeliac wheat sensitivity 4.35 (2.15–9.80) -
Medical co-morbidities
Asthma - 3.02 (1.44–6.34) -
Allergic rhinitis - 1.45 (1.01–2.08)
Migraine 1.53 (1.06–2.21) -
IBS (diagnostic code) 1.85 (1.21–2.82) -
Rheumatoid Arthritis - 3.93 (1.28–12.06) -
Diabetes Mellitus 2.64 (1.20–5.81)
Psychiatric comorbidities
Major depression (diagnostic code) 1.47 (1.02–2.11) - -
HADS- Depression 1.10 (1.05–1.16) - 1.10 (1.05–1.16)
HADS- Anxiety - 1.22 (1.12–1.32) -
SSC 1.07 (1.04–1.10) - -

Abbreviations: IBS: irritable bowel syndrome. HADS: Hospital Anxiety and Depression Scale. SSC: Somatic Symptom Checklist.