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. 2024 Feb 1;29(5):2300244. doi: 10.2807/1560-7917.ES.2024.29.5.2300244

Table 2. Categorisation of seasonality methods included in the systematic review and their definition of the start and end of the respiratory syncytial virus (RSV) season, 2016−2021 (n = 32 articles).

Data requirement Timing Name Start End Source
Denominator Real-time (potential) I: % positivity threshold 1st or 1st of 2 consecutive weeks when positivity exceeds threshold (thresholds used; 3,5, 7 or 10%) Last or last of 2 consecutive weeks with positivity above threshold [13,22,23,27,40,44,47,48,52,54,55,57,62]
II: MEM 1st week when curve exceeds the epidemic threshold (based on historical surveillance data) 1st week when curve is below the post-epidemic threshold (based on historical surveillance data) [12,13,43]
Retrospective III: mean positivity threshold Various (e.g. 1st of 3 consecutive weeks or 1st week with percentage positive exceeding mean positivity threshold) Various (e.g. 3rd of 3 consecutive weeks that occur at least 5 weeks following season onset, where the percentage positive is below the mean positivity threshold) [26,51,59]
Numerator Real-time (potential) IV: Number of detections threshold Various (e.g. 1st week with at least 20 detections, 3 consecutive weeks with at least 6 RSV hospitalisations per week, RS10, 10-fold baseline) Various (e.g. last week with at least 20 detections or 3 weeks with 6 or more RSV hospitalisations consecutively) [12,20,22,58]
II: MEM 1st week when curve exceeds the epidemic threshold (based on historical surveillance data) 1st week when curve is below the post-epidemic threshold (based on historical surveillance data) [12,13,43]
V: change point analysis No formal definition, modelled via change point analysis No formal definition, modelled via change point analysis [56]
Retrospective VI: % of detections threshold Various (e.g. 1st week RSV detections exceed 1.2% of total RSV positive specimens) Various (e.g. last week RSV detections exceed 1.2% of total RSV positive specimens) [12,13,25,50,53,58]
VII: mean detections threshold Various (e.g. above the average weekly number of cases, 60% threshold) Various (e.g. below the average weekly number of cases, 60% threshold) [13,45,60,61]
VIII: AAP 1st month of the longest period of consecutive months to be included in the sorted AAP 75% Last month of the longest period of consecutive months to be included in the sorted AAP 75% [1]

AAP: average annual percentage. MEM: moving epidemic method. RSV: respiratory syncytial virus; RS10: retrospective slope 10.