Fig. 5. Superpositions of 1-deoxynojirimycin (23): (A) acyclic analogue 24: (B) salacinol (1): (C) neosalacinol (4): (D) acyclic analogues 26c: (E) and 27c: (F) in the hNtMGAM active site. Double-headed dot arrows show hydrogen bonding (white) and salt bridge (yellow) residues with amino acid residues. Double-headed orange arrows show distances between side chain carbons and amino acid residues (Asp327 and Asp524). The numbers attached to arrows indicate the binding distance (Å).
