TABLE 1.
Binding and infection of untreated and differentiated HL-60 cells following HGE inoculation
| Inducing agent | Bacteria bound/cella | Cells infected (%)b
|
|
|---|---|---|---|
| 48 h | 7 days | ||
| None | 4.2 ± 1.4 | 29 | >99 |
| Granulocytic inducers | |||
| DMSO | 8.6 ± 3.2c | 70d | >99 |
| RA | NDe | 38 | >99 |
| Monocytic inducers | |||
| TPA | 2.0 ± 0.8d | 0d | 0d |
| γ-IFN | 3.0 ± 2.9 | 10d | 1d |
| VD3 | 3.4 ± 2.6 | 21f | >99 |
a
Mean ± standard deviation (four samples per group).
b
Mean percentage of cells infected (four samples per group).
c
P = 0.07 compared with untreated controls, Student’s t test.
d
P < 0.05 compared with untreated controls, Student’s t test.
e
ND, not done.
f
P = not significant compared with other monocytic inducers and control uninduced cells.