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[Preprint]. 2024 Jan 19:rs.3.rs-3873029. [Version 1] doi: 10.21203/rs.3.rs-3873029/v1

Figure 1. Neutralizing GM-CSF auto-Abs in patients with cryptococcosis by Cryptococcus gattii.

Figure 1

STAT5 phosphorylation (p-STAT5), assessed by flow cytometry, upon the stimulation with recombinant human rhGM-CSF (red) or rhIL-3 (black) of control PBMCs, in the absence of sera, or in the presence of 1:10 dilution of sera from two healthy individuals (HC-1 and HC-2), sera of two individuals previously described carrying GM-CSF auto-Abs (C-1 and C-2) or from thirteen patients with cryptococcosis by C. gattii. NS: non-stimulated with rhGM-CSF or rhIL-3.