Table 1.
Combined |
Female |
Male |
|||||||
---|---|---|---|---|---|---|---|---|---|
COVID-19 Positive | Negative Control | p Value | COVID-19 Positive | Negative Control | p Value | COVID-19 Positive | Negative Control | p Value | |
N | 61 | 61 | – | 24 | 24 | – | 37 | 37 | – |
Age, yrs | 20 ± 1 | 20 ± 2 | 0.8 | 19 ± 1 | 19 ± 1 | 0.6 | 21 ± 1 | 21 ± 2 | >0.9 |
Sex, % women | 39 | 39 | – | – | – | – | – | – | – |
BMI, kg/m2 | 27 ± 5 | 25 ± 3 | 0.2 | 23 ± 4 | 24 ± 2 | 0.8 | 29 ± 5 | 27 ± 4 | 0.04 |
Days since diagnosis | 40 ± 38 | – | – | 51 ± 43 | – | – | 31 ± 32 | – | – |
Vital signs | |||||||||
SBP, mmHg | 122 ± 11 | 127 ± 12 | 0.2 | 120 ± 10 | 122 ± 10 | 0.5 | 124 ± 11 | 130 ± 12 | 0.1 |
DBP, mmHg | 63 ± 8 | 63 ± 7 | 0.8 | 62 ± 7 | 62 ± 6 | 0.9 | 63 ± 9 | 64 ± 7 | 0.7 |
LVmass, g | 204 ± 62 | 207 ± 62 | 0.82 | 168 ± 54 | 172 ± 51 | 0.8 | 228 ± 56 | 229 ± 59 | 0.9 |
LVSV | 76 ± 19 | 73 ± 16 | 0.36 | 65 ± 14 | 66 ± 17 | 0.8 | 84 ± 18 | 78 ± 14 | 0.15 |
IVSDd, mm | 1.0 ± 0.2 | 1.1 ± 0.2 | 0.07 | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.7 | 1.1 ± 0.2 | 1.2 ± 0.2 | 0.04 |
PWDd, mm | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.6 | 1.0 ± 0.2 | 1.0 ± 0.2 | 0.8 | 1.1 ± 0.2 | 1.1 ± 0.2 | 0.4 |
RWT | 0.42 ± 0.08 | 0.48 ± 0.08 | 0.2 | 0.43 ± 0.09 | 0.43 ± 0.07 | >0.9 | 0.41 ± 0.08 | 0.45 ± 0.09 | 0.07 |
LVM, g | 204 ± 92 | 206 ± 62 | 0.8 | 168 ± 54 | 172 ± 50 | 0.4 | 228 ± 55 | 227 ± 59 | >0.9 |
LVMi, g/ m2 | 96 ± 22 | 101 ± 25 | 0.3 | 90 ± 22 | 95 ± 22 | 0.6 | 100 ± 22 | 106 ± 24 | 0.4 |
LVEDD, cm | 5.0 ± 0.6 | 4.8 ± 0.4 | 0.1 | 4.6 ± 0.5 | 4.6 ± 0.4 | >0.9 | 5.2 ± 0.5 | 5.0 ± 0.4 | 0.01 |
LVEDDi, cm/m2 | 2.4 ± 0.3 | 2.4 ± 0.3 | 0.2 | 2.6 ± 0.4 | 2.6 ± 0.3 | 0.4 | 2.3 ± 0.2 | 2.3 ± 0.2 | 0.3 |
LVEDV, ml | 127 ± 33 | 118 ± 24 | 0.19 | 107 ± 19 | 103 ± 20 | 0.5 | 140 ± 33 | 127 ± 21 | 0.09 |
LVEDVi, ml/m2 | 60 ± 11 | 58 ± 9 | 0.5 | 59 ± 10 | 57 ± 9 | 0.6 | 62 ± 12 | 59 ± 8 | 0.6 |
LVEF, % | 65 ± 6 | 72 ± 8 | <0.0001 | 67 ± 6 | 72 ± 8 | 0.02 | 64 ± 6 | 72 ± 8 | <0.001 |
LVEF <50%, % | 0 | 0 | >0.9 | 0 | 0 | >0.9 | 0 | 0 | >0.9 |
SV, ml | 76 ± 19 | 73 ± 16 | 0.4 | 65 ± 13 | 66 ± 16 | 0.4 | 84 ± 18 | 78 ± 14 | 0.2 |
SV, ml/m2 | 36.4 ± 7 | 37 ± 7 | 0.9 | 36 ± 8 | 36 ± 9 | >0.9 | 37 ± 7 | 37 ± 6 | >0.9 |
E | 0.86 ± 0.15 | 0.90 ± 0.15 | 0.13 | 0.88 ± 0.1 | 0.96 ± 0.15 | 0.2 | 0.84 ± 0.17 | 0.86 ± 0.13 | 0.4 |
A | 0.45 ± 0.10 | 0.4 ± 0.09 | 0.08 | 0.4 ± 0.06 | 0.41 ± 0.10 | 0.4 | 0.47 ± 0.12 | 0.41 ± 0.08 | 0.07 |
E/A | 2.00 ± 0.5 | 2.3 ± 0.52 | 0.006 | 2.2 ± 0.4 | 2.4 ± 0.6 | 0.2 | 1.89 ± 0.48 | 2.14 ± 0.47 | 0.008 |
Septal e’ | 0.16 ± 0.16 | 0.14 ± 0.03 | 0.3 | 0.13 ± 0.02 | 0.14 ± 0.02 | 0.3 | 0.18 ± 0.2 | 0.14 ± 0.02 | 0.3 |
Septal s’ | 0.09 ± 0.01 | 0.09 ± 0.02 | 0.8 | 0.08 ± 0.01 | 0.08 ± 0.01 | 0.8 | 0.09 ± 0.02 | 0.10 ± 0.03 | 0.6 |
E/e’ | 6.6 ± 1.7 | 6.7 ± 1.6 | 0.6 | 6.6 ± 1.2 | 6.9 ± 1.8 | 0.7 | 6.7 ± 1.9 | 6.5 ± 1.5 | 0.6 |
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; IVSDd: intraventricular septum diastolic dimension; PWDd: posterior wall diastolic dimension; RWT: relative wall thickness; LVmass: left-ventricular mass; LVEDD: left-ventricular end-diastolic diameter; LVEDV: left-ventricular end-diastolic volume; LVESV: left-ventricular end-systolic volume; LVEF: left-ventricular ejection fraction; SV: stroke volume.