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. 2023 Oct 24;29(2):e248–e258. doi: 10.1093/oncolo/oyad283

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Representative hematoxylin and eosin (H&E) images of different tumor-infiltrating lymphocytes (TILs) density and tertiary lymphoid structures (TLSs) subtypes. (A: TILs = 20%; B: TILs = 40%; C: TILs = 60%; D: TILs = 80%; E: nGC TLSs; F: GC TLSs; A-F: 40x; E and F Insert:200×). Representative immunohistochemistry (IHC) images of non-germinal center (nGC) TLS and germinal center (GC) TLS (nGC TLS: G: CD20 + B cells; H: CD3 + T cells; GC TLS: I: CD20 + B cells; J: CD3 + T cells; K: Bcl-6 + GC B cells; L: CD21 + FDCs; 200×).