Table 1.
Comparison of TILs density and TLSs in NMIBC and MIBC.
| Clinicopathological | All | NMIBC | MIBC | P |
|---|---|---|---|---|
| Characteristics | (580, 100%) | (313, 54.0%) | (267, 46.0%) | |
| TLSs | ||||
| Positive | 332(57.2) | 151(48.2) | 181(67.8) | <.001 |
| Negative | 248(42.8) | 162(51.8) | 86(32.2) | |
| nGC TLS | ||||
| Positive | 260(44.8) | 113(36.1) | 147(55.1) | <.001 |
| Negative | 320(55.2) | 200(63.9) | 120(44.9) | |
| GC TLS | ||||
| Positive | 72(12.4) | 38(12.1) | 34(12.7) | .829 |
| Negative | 508(87.6) | 275(87.9) | 233(87.3) | |
| TILs | ||||
| Median/range | 15/1-90 | 10/1-85 | 20/1-90 | <.001 a |
| Mean ± SD | 20.5 ± 17.0 | 17.5 ± 16.2 | 24.0 ± 17.2 |
P value bolded: P < 0.05.
a: t-test; other testing methods are chi-square test.
Abbreviations: GC TLS: germinal center TLS; MIBC: muscle-invasive bladder cancer; nGC TLS: non-germinal center TLS; NMIBC: non-muscle invasive bladder cancer; TILs: tumor-infiltrating lymphocytes; TLSs: tertiary lymphoid structures.