Figure 3. RNA-Seq of RAB7-silenced PAECs.

Ingenuity Pathway Analysis of bulk RNA-Seq data in PAECs transfected with RAB7 siRNA versus control siRNA (fold change >|1.25|, adjusted P value <0.05) (representing n = 3 per group). The diagram lists the 30 most regulated function terms and shows the number of DEGs in the RNA-Seq data set within each category. DEG terms were labeled according to their relevance for cell-cycle and DNA repair (blue), cellular movement and trafficking (orange), immune function and inflammation (green), and development (red).