Table 1.
Baseline characteristics
| Group 1: before introduction of the algorithm (N = 14) | Group 2: following introduction of the algorithm (N = 16) | p value | |
|---|---|---|---|
| Age, years | 53 (37–58) | 57.5 (44.5–60.5) | 0.405 |
| Male, % | 64.3% | 68.8% | 0.550 |
| Preoperative MELD-Na | 22 (14–34) | 21 (10.8–30.5) | 0.677 |
| Transplant indication | |||
| Hepatocellular carcinoma, n | 3 | 3 | 0.287 |
| Viral disease, n | 1 | 1 | |
| Autoimmune hepatitis, n | 3 | 6 | |
| Alcoholic cirrhosis, n | 2 | 1 | |
| Non-alcoholic cirrhosis, n | 1 | 4 | |
| Biliary disease, n | 2 | 0 | |
| Other, n | 2 | 1 | |
| Patient history and comorbidities | |||
| McKluskey index | 2 (1–2.75) | 2 (1–3) | 0.491 |
| Anaemia, n | 10 | 11 | 0.569 |
| Preoperative thrombocytopaenia, n | 11 | 12 | 0.999 |
| Preoperative AKI, n | 5 | 3 | 0.263 |
| Diabetes mellitus, n | 5 | 9 | 0.225 |
| History of malignancy, n | 7 | 5 | 0.251 |
| Hospitalization within the last month, n | 8 | 11 | 0.706 |
| Previous abdominal surgery, n | 8 | 11 | 0.706 |
| Preoperative laboratory tests and others | |||
| Albumin, g/dL | 3.4 (2.8–4.0) | 3.5 (2.8–3.6) | 0.480 |
| Creatinine, mg/dL | 1.0 (0.8–1.2) | 0.7 (0.6–0.9) | 0.061 |
| Haemoglobin, g/dL | 10.3 (8.5–12.8) | 12.2 (8.9–13.3) | 0.454 |
| Platelet count, ×1,000/μL | 68 (48–96) | 46.5 (39.5–97.5) | 0.533 |
| Plasma fibrinogen, mg/dL | 139 (75–202) | 167 (129–195) | 0.358 |
| INR | 1.9 (1.2–2.6) | 1.8 (1.5–2.2) | 0.950 |
| Total ischaemia time, min | 367 (267–456) | 320 (265.5–407.5) | 0.637 |
| Donor risk index | 1.96 (1.60–2.09) | 1.88 (1.45–2.31) | 0.992 |
| Patients receiving any blood product preoperativelya, n | 4 | 5 | 0.999 |
Data are shown as median (inter-quartile range), unless indicated otherwise.
INR, international normalized ratio; AKI, acute kidney injury.
aFrom last hospital admission to completion of liver transplantation.