Table 2.
Haemostatic agents transfused in the first 24 h and 7 days following the start of surgery, in patients treated before and after introduction of the haemostatic algorithm
| Group 1: before introduction of the algorithm (N = 14) | Group 2: following introduction of the algorithm (N = 16) | p value | |
|---|---|---|---|
| 24 h following the start of surgery | |||
| Total blood products transfused, U | 33 (11–57) | 1.5 (0–23.5) | 0.028 |
| Patients receiving any blood product, n (%) | 12 (85.7) | 8 (50) | 0.057 |
| RBCs, U | 5 (2–10) | 0.5 (0–5) | 0.035 |
| Patients receiving RBC, n (%) | 11 (68.7) | 6 (37.5) | 0.032 |
| FFP, U | 4 (0–6) | 0 (0–1.5) | 0.024 |
| Patient receiving FFP, n (%) | 9 (64.2) | 4 (25) | 0.063 |
| Aphaeresis platelets, U | 1 (0–2) | 0.5 (0–1) | 0.560 |
| Patients receiving PC, n (%) | 8 (57.1) | 8 (50) | 0.730 |
| Cryoprecipitate, U | 21 (3–42) | 0 (0–13.5) | 0.043 |
| Patients receiving CP, n (%) | 11 (78.5) | 7 (43.7) | 0.071 |
| Fibrinogen concentrate, g | 0 (0–0) | 2.5 (1–5) | <0.001 |
| Patients receiving FC, n (%) | 0 (0) | 12 (75) | <0.001 |
| PPC, IU | 0 (0–0) | 1 (0–2) | 0.073 |
| Patients receiving PPC, n (%) | 3 (21.4) | 9 (56.2) | 0.071 |
| Tranexamic acid, g | 0 (0–0) | 2 (1–2) | <0.001 |
| Patients receiving TXA, n (%) | 1 (7.1) | 14 (87.5) | <0.001 |
| 7 days following the start of surgery | |||
| Total blood products transfused, U | 36 (11–63) | 4.5 (0–34) | 0.062 |
| Patients receiving any blood product, n (%) | 12 (85.7) | 8 (50) | 0.057 |
| RBCs, U | 6 (2–12) | 1.5 (0–8.5) | 0.198 |
| Patients receiving RBC, n (%) | 11 (68.7) | 8 (50) | 0.419 |
| FFP, U | 4.5 (0–8) | 0 (0–1.5) | 0.026 |
| Patient receiving FFP, n (%) | 9 (64.2) | 4 (25) | 0.063 |
| Aphaeresis platelets, U | 1 (0–3) | 1 (0–1) | 0.692 |
| Patients receiving PC, n (%) | 8 (57.1) | 9 (56.2) | 0.999 |
| Cryoprecipitate, U | 21 (3–42) | 0 (0–13.5) | 0.043 |
| Patients receiving Cryo, n (%) | 11 (78.5) | 7 (43.7) | 0.071 |
| Fibrinogen concentrate, g | 0 (0–0) | 2.5 (1–5) | <0.001 |
| Patients receiving FC, n (%) | 0 (0) | 12 (75) | <0.001 |
| PPC, IU | 0 (0–0) | 1 (0–2) | 0.073 |
| Patients receiving PPC, n (%) | 3 (21.4) | 9 (56.2) | 0.071 |
| Tranexamic acid, g | 0 (0–0) | 2 (1–2) | <0.001 |
| Patients receiving TXA, n (%) | 1 (7.1) | 14 (87.5) | <0.001 |
The amounts of transfusions are detailed only for transfused patients. Data are shown as median (inter-quartile range) or as numbers and percentages. Values in bold are where p < 0.05. Cryo, cryoprecipitate; FC, fibrinogen concentrate; FFP, fresh frozen plasma; PC, platelet aphaeresis concentrate; PPC, prothrombin complex concentrate; RBC, red blood cells; TXA, tranexamic acid.