Table 6.

Effect of Ocimum gratissimum Linn. leaf extract (OG), OG petroleum ether fraction (PEOG), OG ethyl acetate fraction (EAOG), OG ethanol fraction (EOG) and valsartan-lisinopril fixed dose combination on the plasma cardiac troponin I (cTnI) levels in TZM-intoxicated rats.

Treatment Groups	Plasma cardiac troponin I levels (ng/ml)
Veh.	04.62 ± 01.35
Veh. + TZM	13.21 ± 01.80c+
OG	01.77 ± 00.84c-
OG + TZM	08.85 ± 04.51a+
PEOG	03.99 ± 01.07a-
PEOG + TZM	02.86 ± 01.87a-
EAOG	03.18 ± 00.93a-
EAOG + TZM	02.32 ± 01.21c-
EOG	01.75 ± 00.36c-
EOG + TZM	02.16 ± 01.23a-
VAL-LSP	01.39 ± 00.26c-
VAL-LSP + TZM	01.46 ± 00.51c-

^c+ represents a significant increase at p < 0.05 when compared to values for the Veh.only-treated group while ^a- and ^c- represent significant decreases at p < 0.05 and p < 0.001 when compared to values for the Veh. + TZM-treated group

Veh. – 10 ml/kg/day distilled water p.o. + 1 ml/kg/day distilled water i.p.

Veh. + TZM – 10 ml/kg/day distilled water p.o. + 2.25 mg/kg/day TZM i.p.

OG – 100 mg/kg/day OG p.o. + 1 ml/kg/day distilled water i.p.

OG + TZM – 100 mg/kg/day OG p.o. + 2.25 mg/kg/day TZM i.p.

PEOG – 100 mg/kg/day PEOG p.o. + 1 ml/kg/day distilled water i.p.

PEOG + TZM - 100 mg/kg/day PEOG p.o. + 2.25 mg/kg/day TZM i.p.

EAOG - 100 mg/kg/day EAOG p.o. + 1 ml/kg/day distilled water i.p.

EAOG + TZM - 100 mg/kg/day EAOG p.o. + 2.25 mg/kg/day TZM i.p.

EOG - 100 mg/kg/day EOG p.o. + 1 ml/kg/day distilled water i.p.

EOG + TZM - 100 mg/kg/day EOG p.o. + 2.25 mg/kg/day TZM i.p.

VAL-LSP – 5 mg/kg/day VAL-0.035 mg/kg/day LSP fixed-dose combination p.o. + 1 ml/kg/day distilled water i.p.

VAL-LSP + TZM – 5 mg/kg/day VAL-0.035 mg/kg/day LSP fixed-dose combination p.o. + 2.25 mg/kg/day TZM i.p.