Table 4.
Univariate and multivariate analysis for infection of MDS
| Parameter | Univariate | Multivariate | |
|---|---|---|---|
| p-value | p-value | HR (95%CI) | |
| Age, year | 0.000 | 0.009 | 1.506 (1.120–2.086) |
| (> 60 vs. ≤ 60) | |||
| WBC, 10^9/L | 0.059 | 0.041 | 1.451 (1.014–2.074) |
| ANC, 10^9/L | 0.025 | 0.721 | 0.983 (0.895–1.080) |
| (< 0.8 vs. ≥ 0.8) | |||
| HGB, g/L | 0.147 | ||
| PLT, 10^9/L | 0.078 | 0.212 | 1.262 (0.875–1.820) |
| (< 50 vs. 50− < 100 vs. ≥ 100) | |||
| Serum ferritin, ng/ml | 0.001 | 0.003 | 1.613 (1.171–2.220) |
| (> 500 vs. ≤ 500) | |||
| Erythropoietin, mIU/ml | 0.219 | ||
| (≤ 500 vs. > 500) | |||
| BM blasts percentage,% | 0.000 | 0.000 | 1.503 (1.287–1.755) |
| (> 10 vs.5–10 vs. > 2− < 5 vs. ≤ 2) | |||
| IPSS-R risk category | |||
| Very low | 0.000 | 0.634 | 1.038 (0.891–1.208) |
| Low | |||
| Intermediate | |||
| High | |||
| Very high | |||
| Cytogenetic | |||
| Very poor | 0.024 | 0.312 | 1.092 (0.921–1.296) |
| Poor | |||
| Intermediate | |||
| Good | |||
| Very good | |||
| Diabetes mellitus | 0.000 | 0.000 | 2.135 (1.451–3.110) |
ANC Absolute neutrophil count; BM bone marrow; HGB homoglobin; HR hazard ratio; IPSS-R revised international prognostic scoring system; PLT platelet; WBC White blood cell count