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Clearance of bacteremia and valvular adherence following simultaneous challenge with tPMPs and tPMPr S. aureus strainsa
| Strain | Bacteremia (mean log10 CFU/ml ± SD)
|
Adherence at 30 min (mean log10 CFU/vegetation ± SD) | |
|---|---|---|---|
| 1 min | 30 min | ||
| ISP479C | 4.95 ± 0.53 | 1.5 ± 0.71 | 1.65 ± 0.42 |
| ISP479R | 4.31 ± 0.67 | 1.73 ± 0.68 | 1.56 ± 0.53 |
Strains (3 × 107 CFU of each) were simultaneously injected via marginal ear veins into eight animals with indwelling transaortic catheters.
