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. 2023 Dec 6;67:102264. doi: 10.1016/j.eclinm.2023.102264

Table 1.

Vulnerability attributes associated with adverse outcomes during pregnancy, childbirth, and the postpartum period in systematic reviews (see Appendix 4 for full characteristics of included studies and references).

Vulnerability attribute Early pregnancy Late pregnancy Childbirth Other outcomes
Threat: deficiencies
 Anaemia Small for gestational age
Low birthweight
Preterm birth
Pre-eclampsia
Neonatal mortality
Postpartum haemorrhage
Infection after caesarean section
 Calcium deficiency Pre-eclampsia
 Socioeconomic status Stillbirth
Preterm birth
Low birthweight
 Homelessness Access to antenatal care Preterm birth
Low birthweight
Birth complications including pre-eclampsia, chorioamnionitis, placental abruption, hypertensive disorders of pregnancy, iron deficiency or other anaemia
Threat: risk exposure
 Intimate partner violence Miscarriage
Access to antenatal care
Termination of pregnancy
Pre-eclampsia
Preterm birth
Low birthweight
Stillbirth
Neonatal mortality
Perinatal depression
Postnatal depressive symptoms
 Disasters Access to antenatal care (pandemic) Stillbirth (pandemic)
Pre-eclampsia (terrorist attack)
Low birthweight (terrorist attack; natural disasters; wildfires)
Reduced institutional delivery (pandemic)
Neonatal mortality (pandemic)
Perinatal depression (earthquakes)
Psychosis
 Political instability/Fragile and conflict-affected state (FCAS) Access to antenatal service Stillbirth
Low birthweight
Congenital birth defects
 Substance misuse Low birthweight
Preterm birth
 Alcohol Low birthweight
Placenta abruption
 Smoking Miscarriage Stillbirth Neonatal mortality
 Mental health Low birthweight
Preterm birth
Barriers
 Adolescent pregnancy Anaemia Pre-eclampsia
Preterm birth
Low birthweight
Fetal distress
Obstructed labour
 Religion and culture Low birthweight (fasting mothers)
Lower placental weight in fasting mothers
Prolonged labour (Female Genital Mutilation (FGM))
Instrumental delivery (FGM)
Postpartum haemorrhage (FGM)
Perineal tears (FGM)
Fetal distress (FGM)
Complications (peripartum hysterectomy; uterine rupture; prolonged labour) associated with faith-based institutions (e.g., spiritual churches)
 Low education Access to antenatal care
Childhood pregnancies
Unintended pregnancies
Stillbirth
Hypertensive disorders in pregnancy
Anaemia
Neonatal mortality
Preparation for birth and emergencies
Breastfeeding
 Primigravida or grand multiparity Pre-eclampsia (primigravida)
Gestational diabetes
Postpartum haemorrhage
Perinatal depression
Uterine rupture
 Migrants Access to antenatal care
Miscarriage
Pre-eclampsia
Low birthweight
Gestational diabetes
Small for gestational age
Stillbirth
Preterm birth
Neonatal mortality
Maternal mortality
Infection
Caesarean section
 Refugees Miscarriage
Access to antenatal service
Stillbirth
Preterm birth
Neonatal mortality
Maternal death (hypertensive disorders, deep vein thrombosis and pre-eclampsia)
Mental health conditions
 Child marriage Reduced institutional delivery Intimate partner violence