Table 2.
The modes of HBOT intervention in the 8 RCTs
| Study | FiO2 | Pressure | Begin time | Treatment time | Therapy duration |
|---|---|---|---|---|---|
| Chen 2012 | 100%O2 | 2ATA | Within 3 ~ 5days after stroke onset | 60 min | qd, 10days |
| Chen 2018 | 100%O2 | 2.5ATA | NR | 60 min | Once |
| Nighoghossian 1995 | 100%O2/air# | 1.5ATA/1.5ATA# | Within 24 h after stroke onset | 40 min/40min# | a total of 10 dives |
| Rusyniak 2003 | 100%O2/100%O2# | 2.5ATA/1.14ATA# | Within 24 h since symptom onset | 60 min/60min# | Once |
| Zhu 2022 | NR | 2ATA | NR | 80 min | q3d, 36days |
| Imai 2006 | 100%O2 | 2ATA | NR | 60 min | qd, 1week |
| Zhao 2008 | 99%O2 | 2ATA | Within 1 ~ 3days following admission | 60 min | qd, 10days |
| Dong 2023 | NR | 2ATA | NR | 60 min | qd, 12weeks* |
IG: interventional group;CG: controlled group; NR: not reported; qd: once a day; q3d: once every 3 days
#Data are given as Treatment/Control
*10 cycles as a treatment course, with an interval of three days between courses