Table 2.
Univariate and Multivariate Analyses of Factors Influencing Effectiveness
| Characteristic | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Age, years | 1.087(1.005–1.176) | 0.038 | 1.07(0.922–1.241) | 0.058 |
| Gender | 1.000(0.300–3.336) | 1.000 | ||
| BMI, kg/m2 | 0.951(0.818–1.106) | 0.514 | ||
| Clinical classification | 10.554(3.912–28.477) | 0.000 | 6.883(1.349–35.108) | 0.020 |
| APACHE II score | 1.610(1.270–2.041) | 0.000 | 1.398(0.989–1.977) | 0.058 |
| eGFR, mL/min | 0.991(0.967–1.017) | 0.499 | ||
| Albumin, g/L | 0.907(0.796–1.037) | 0.144 | ||
| TBil, μmol/L | 1.203(1.045–1.384) | 0.010 | 0.961(0.714–1.294) | 0.792 |
| ALT, U/L | 0.999(0.989–1.010) | 0.890 | ||
| AST, U/L | 1.042(1.014–1.071) | 0.003 | 1.060(0.986–1.139) | 0.115 |
| r-GT, U/L | 1.005(0.997–1.013) | 0.214 | ||
| LDH, U/L | 1.012(1.005–1.018) | 0.001 | 1.003(0.992–1.015) | 0.548 |
| TC, mmol/L | 0.402(0.178–0.910) | 0.029 | 0.232(0.022–2.44) | 0.224 |
| Diabetes | 2.046(0.646–6.482) | 0.224 | ||
| Hypertension | 2.147(0.706–6.523) | 0.178 | ||
| Nirmatrelvir, μg/mL | 1.195(0.999–1.429) | 0.051 | 1.073(0.680–1.695) | 0.762 |
| Ritonavir, μg/mL | 1.572(0.767–3.223) | 0.217 | ||
| Length of stay, days | 1.015(0.970–1.061) | 0.528 | ||
Abbreviations: eGFR, estimated glomerular filtration rate; TBil, total bilirubin; ALT, alanine aminotransferase; AST, aspartate transaminase; r-GT, r-glutamyltransferase; LDH, lactate dehydrogenase; TC, total cholesterol.