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. Author manuscript; available in PMC: 2024 Feb 3.
Published in final edited form as: Toxicol In Vitro. 2021 Feb 18;73:105109. doi: 10.1016/j.tiv.2021.105109

Figure 3. Clearance of 7HC by PHH and three Tox21 cell lines.

Figure 3.

HepG2, HEK293 and MCF7 cells were incubated at 50,000 cells/well for 24 hours individually in comparison to PHHs (50,000 cells/well) incubated with 1.0 μM 7HC at 0,15, 30, 60, 90, 150 and 240 minutes. LC-MS analysis was performed to monitor the clearance of 7HC parent compound at 1.0 μM to derive percent depletion and apparent half-life (t1/2). 7HC clearance in PHHs (A); 7HC clearance in HepG2 cells (B); 7HC clearance in HEK293 cells (C); 7HC clearance in MCF7 cells (D).