. 2024 Feb 3;147(1):31. doi: 10.1007/s00401-023-02678-7

Table 2.

Changes of AQP1 and AQP4 immunoreactivities in the CNS of GFAP autoimmunity

	Normal control	GFAP Autoimmunity (Fig. 8k–o)
AQP1	Cortex < white matter	Normal^a (3/5) Increased (1/5) Focally decreased (1/5)	Increased (4/6) Increased and decreased in different locations (2/6)
AQP4	Cortex > white matter	Normal (1/4) Increased (2/4) Focal perivascular and subpial decreased (1/4)	Increased (5/5)

Normal control

GFAP Autoimmunity (Fig. 8k–o)

Cortex

White matter

AQP1

Cortex < white matter

Normal^a (3/5)

Increased (1/5)

Focally decreased (1/5)

Increased (4/6)

Increased and decreased in different locations (2/6)

AQP4

Cortex > white matter

Normal (1/4)

Increased (2/4)

Focal perivascular and subpial decreased (1/4)

Increased (5/5)

^aNormal, increased and decreased, mean the immunoreactivity compared with normal control tissue

AQP1 aquaporin1, AQP4 aquaporin 4, GFAP glial fibrillary acidic protein