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. 2024 Feb 3;14:2856. doi: 10.1038/s41598-024-52992-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Paclitaxel effect on cells in 2D experiments. SKOV-3 and SKOV-3.tr cells were pre-treated with strain for 24 h, re-plated on tissue culture dishes, and then treated with paclitaxel for 24 h prior to analysis for HSP27 (A) or cleaved caspase-3 (B). Fluorescence was normalized to DAPI fluorescence. (C) Cells pre-treated with 24 h strain followed by paclitaxel treatment were also analyzed via Sytox staining for cell death. Data shown as average + SEM; N = 3 samples. *p < 0.05. Samples were compared with ANOVA and post-hoc Tukey HSD tests.