Table 5.
Seminogram categories | TGF- β1 | Infertile males’ frequency (N/%) | Fertile males’ frequency (N/%) | RR | Preventive Fraction | P | 95% CI |
---|---|---|---|---|---|---|---|
Normozoospermia | Genotype | ||||||
CC | 8 (28.57%) | 16 (40%) | 0.60 | 0.6 | 0.41 | 0.22-1.66 | |
CT | 19 (67.86%) | 23 (57.5%) | 1.56 | 0.24 | 0.45 | 0.58-4.22 | |
TT | 1 (3.57%) | 1 (2.5%) | 1.44 | 0.01 | 1.00 | 0.09-23.09 | |
(CC+CT) vs TT | 27 (96.43%) | 39 (97.5%) | 0.69 | 0.3 | 1.00 | 0.04-11.07 | |
(TT+CT) vs CC | 20 (71.43%) | 24 (60.0%) | 1.67 | 0.28 | 0.44 | 0.60-4.62 | |
Allele | |||||||
C allele | 35 (62.5%) | 55 (68.75%) | 0.76 | 0.16 | 0.46 | 0.37-1.55 | |
T allele | 21 (37.5%) | 25 (31.25%) | 1.32 | 0.09 | 0.46 | 0.65-2.69 | |
Oligozoospermia | Genotype | ||||||
CC | 39 (51.32%) | 16 (40%) | 1.58 | 0.18 | 0.32 | 0.73-3.41 | |
CT | 35 (46.05%) | 23 (57.5%) | 0.63 | 0.21 | 0.32 | 0.29-1.35 | |
TT | 2 (2.63%) | 1 (2.5%) | 1.05 | 0.001 | 1.00 | 0.10-11.69 | |
(CC+CT) vs TT | 74 (97.37%) | 39 (97.5%) | 0.95 | 0.05 | 1.00 | 0.09-10.52 | |
(TT+CT) vs CC | 37 (48.68%) | 24 (60.0%) | 0.63 | 0.22 | 0.32 | 0.29-1.36 | |
Allele | |||||||
C allele | 113 (74.34%) | 55 (68.75%) | 1.32 | 0.17 | 0.44 | 0.73-2.38 | |
T allele | 39 (25.66%) | 25 (31.25%) | 0.76 | 0.07 | 0.44 | 0.42-1.37 | |
Azoospermia | Genotype | ||||||
CC | 28 (70%) | 16 (40%) | 3.50 | 0.5 | 0.013* | 1.40-8.73 | |
CT | 10 (25%) | 23 (57.5%) | 0.25 | 0.43 | 0.006** | 0.10-0.63 | |
TT | 2 (5%) | 1 (2.5%) | 2.05 | 0.02 | 1.00 | 0.18-22.88 | |
(CC+CT) vs TT | 38 (95%) | 39 (97.5%) | 0.49 | 0.5 | 1.00 | 0.04-5.43 | |
(TT+CT) vs CC | 12 (30%) | 24 (60.0%) | 0.29 | 0.42 | 0.013* | 0.11-0.71 | |
Allele | |||||||
C allele | 66 (82.5%) | 55 (68.75%) | 2.14 | 0.44 | 0.06 | 1.02-4.50 | |
T allele | 14 (17.5%) | 25 (31.25%) | 0.47 | 0.16 | 0.06 | 0.22-0.98 |
RR: Relative risk, CI: Confidence Intervals, Exact Fishers Probability (P).