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. 2023 Jul;12(2):318–331. doi: 10.61186/rbmb.12.2.318

Table 5.

The genotypes and alleles frequencies of TGF-β1 +869 C/T in the fertile and infertile male categories.

Seminogram categories TGF- β1 Infertile males’ frequency (N/%) Fertile males’ frequency (N/%) RR Preventive Fraction P 95% CI
Normozoospermia Genotype
CC 8 (28.57%) 16 (40%) 0.60 0.6 0.41 0.22-1.66
CT 19 (67.86%) 23 (57.5%) 1.56 0.24 0.45 0.58-4.22
TT 1 (3.57%) 1 (2.5%) 1.44 0.01 1.00 0.09-23.09
(CC+CT) vs TT 27 (96.43%) 39 (97.5%) 0.69 0.3 1.00 0.04-11.07
(TT+CT) vs CC 20 (71.43%) 24 (60.0%) 1.67 0.28 0.44 0.60-4.62
Allele
C allele 35 (62.5%) 55 (68.75%) 0.76 0.16 0.46 0.37-1.55
T allele 21 (37.5%) 25 (31.25%) 1.32 0.09 0.46 0.65-2.69
Oligozoospermia Genotype
CC 39 (51.32%) 16 (40%) 1.58 0.18 0.32 0.73-3.41
CT 35 (46.05%) 23 (57.5%) 0.63 0.21 0.32 0.29-1.35
TT 2 (2.63%) 1 (2.5%) 1.05 0.001 1.00 0.10-11.69
(CC+CT) vs TT 74 (97.37%) 39 (97.5%) 0.95 0.05 1.00 0.09-10.52
(TT+CT) vs CC 37 (48.68%) 24 (60.0%) 0.63 0.22 0.32 0.29-1.36
Allele
C allele 113 (74.34%) 55 (68.75%) 1.32 0.17 0.44 0.73-2.38
T allele 39 (25.66%) 25 (31.25%) 0.76 0.07 0.44 0.42-1.37
Azoospermia Genotype
CC 28 (70%) 16 (40%) 3.50 0.5 0.013* 1.40-8.73
CT 10 (25%) 23 (57.5%) 0.25 0.43 0.006** 0.10-0.63
TT 2 (5%) 1 (2.5%) 2.05 0.02 1.00 0.18-22.88
(CC+CT) vs TT 38 (95%) 39 (97.5%) 0.49 0.5 1.00 0.04-5.43
(TT+CT) vs CC 12 (30%) 24 (60.0%) 0.29 0.42 0.013* 0.11-0.71
Allele
C allele 66 (82.5%) 55 (68.75%) 2.14 0.44 0.06 1.02-4.50
T allele 14 (17.5%) 25 (31.25%) 0.47 0.16 0.06 0.22-0.98

RR: Relative risk, CI: Confidence Intervals, Exact Fishers Probability (P).