FIG. 1.

Growth containment of virulent M. tuberculosis H37Rv organisms induced in peritoneal macrophages by M. tuberculosis H37Ra-primed lymphocytes. Peritoneal macrophages were infected with live, dispersed virulent M. tuberculosis H37Rv at 37°C for 2 to 4 h and then cocultured for 7 days with different numbers of syngeneic splenocytes derived from M. tuberculosis H37Ra-vaccinated and nonvaccinated inbred strain 2 guinea pigs. The cultures were harvested and streaked onto M7H10 agar plates. After 3 weeks of incubation, the CFU were counted. The means ± standard errors of the means for four animals in each group are shown.