Fig. 3.

Important brain regions in MRI and FDG–PET-based 3D CNN models. A–D Feature importance scores of top five brain regions for ADAS–Cog13 sub-scores Q1, Q4, Q7, and Q8 in the MRI-based CNN. E–H Feature importance scores of top five brain regions for Q1, Q4, Q7, and Q8 in FDG–PET-based CNN. I–L Coronal views of top five important brain regions for each ADAS–Cog13 sub-scores in the MRI (red) and the FDG–PET (green) 3D CNNs. Regions that are important for both MRI and FDG–PET models are highlighted in yellow color