Table 1.
Before Matching | After Matching | |||||
---|---|---|---|---|---|---|
Characteristic Name | HIV + | HIV - | p-Value | HIV + | HIV - | p-Value |
N | 13214 | 3016126 | 13212 | 13212 | ||
Age | 49.38 ± 13.71 | 48.43 ± 18.2 | <0.001 | 49.38 ± 13.71 | 49.5 ± 15.59 | 0.506 |
At least 50 years | 6977 (52.8%) | 1424498 (47.2%) | <0.001 | 6975 (52.8%) | 6990 (52.9%) | 0.853 |
At least 65 years | 1773 (13.4%) | 670155 (22.2%) | <0.001 | 1773 (13.4%) | 1786 (13.5%) | 0.815 |
BMI | 28.58 ± 6.73 | 29.72 ± 7.04 | <0.001 | 28.58 ± 6.74 | 29.84 ± 7.09 | <0.001 |
At least 25 kg/m2 | 4075 (30.8%) | 825539 (27.4%) | <0.001 | 2414 (34.2%) | 28 (35.0%) | <0.001 |
At least 30 kg/m2 | 2538 (19.2%) | 546423 (18.1%) | 0.001 | 4073 (30.8%) | 4061 (30.7%) | 0.873 |
Sex | ||||||
Male | 8989 (68.0%) | 1253606 (41.6%) | <0.001 | 8987 (68.0%) | 9018 (68.3%) | 0.682 |
Female | 4223 (32.0%) | 1732998 (57.5%) | <0.001 | 4223 (32.0%) | 4193 (31.7%) | 0.692 |
Unknown | 10 (0.1%)* | 29522 (1.0%) | <0.001 | 10 (0.1%)* | 10 (0.1%)* | 1.000 |
Race | ||||||
Black or African American |
5737 (43.4%) | 502171 (16.7%) | <0.001 | 5735 (43.4%) | 5735 (43.4%) | 1.000 |
White | 4783 (36.2%) | 1790465 (59.4%) | <0.001 | 4783 (36.2%) | 4778 (36.2%) | 0.949 |
Unknown Race | 2469 (18.7%) | 633157 (21.0%) | <0.001 | 2469 (18.7%) | 2455 (18.6%) | 0.825 |
Asian | 146 (1.1%) | 72796 (2.4%) | <0.001 | 146 (1.1%) | 155 (1.2%) | 0.602 |
American Indian or Alaska Native |
63 (0.5%) | 12228 (0.4%) | 0.198 | 63 (0.5%) | 70 (0.5%) | 0.543 |
Native Hawaiian or Other Pacific Islander |
16 (0.1%) | 5309 (0.2%) | 0.133 | 16 (0.1%) | 19 (0.1%) | 0.612 |
Ethnicity | ||||||
Not Hispanic or Latino | 8749 (66.2%) | 1744596 (57.8%) | <0.001 | 8749 (66.2%) | 8776 (66.4%) | 0.725 |
Hispanic or Latino | 1554 (11.8%) | 250600 (8.3%) | <0.001 | 1552 (11.7%) | 1535 (11.6%) | 0.745 |
Unknown Ethnicity | 2911 (22.0%) | 1020930 (33.8%) | <0.001 | 2911 (22.0%) | 2901 (22.0%) | 0.882 |
Comorbid conditions | ||||||
Hypertensive diseases | 6910 (52.3%) | 890736 (29.5%) | <0.001 | 6908 (52.3%) | 6952 (52.6%) | 0.588 |
Neoplasms | 4979 (37.7%) | 618799 (20.5%) | <0.001 | 4977 (37.7%) | 4958 (37.5%) | 0.809 |
Hyperlipidemia | 4517 (34.2%) | 585172 (19.4%) | <0.001 | 4515 (34.2%) | 4514 (34.2%) | 0.990 |
Overweight and obesity | 3693 (27.9%) | 568424 (18.8%) | <0.001 | 3693 (28.0%) | 3724 (28.2%) | 0.671 |
Diabetes mellitus | 3198 (24.2%) | 418044 (13.9%) | <0.001 | 3196 (24.2%) | 3213 (24.3%) | 0.807 |
Chronic kidney disease | 2540 (19.2%) | 194677 (6.5%) | <0.001 | 2538 (19.2%) | 2529 (19.1%) | 0.888 |
Ischemic heart diseases | 2245 (17.0%) | 283916 (9.4%) | <0.001 | 2244 (17.0%) | 2243 (17.0%) | 0.987 |
COPD | 1482 (11.2%) | 145494 (4.8%) | <0.001 | 1481 (11.2%) | 1455 (11.0%) | 0.611 |
Organ Transplant History | 458 (3.5%) | 37406 (1.2%) | <0.001 | 458 (3.5%) | 459 (3.5%) | 0.973 |
Laboratory findings | ||||||
CD4,/mL | 585 ± 383 | 585 ± 383 | ||||
At most 200/uL | 2414 (34.2%) | 2414 (34.2%) | ||||
HIV 1 RNA (viral load) | 17591 ± 95842 | 17591 ± 95842 | ||||
At most 50 {copies}/mL | 1018 (77.7%) | 1018 (77.7%) | ||||
COVID-19 vaccine | 989 (7.5%) | 120460 (4.0%) | <0.001 | 989 (7.5%) | 689 (5.2%) | 0.093 |
*TriNetX automatically round patient counts of 1-9, up to 10.