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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: J Heart Lung Transplant. 2023 Aug 5;42(12):1666–1677. doi: 10.1016/j.healun.2023.08.001

Figure 5. CD4+Granzyme B+ T cells in those with ST.

Figure 5.

(A) Representative flow cytometry plot showing interferon gamma (IFNγ), tumor necrosis factor alpha (TNFα), and granzyme B (top) as well as co-expression (bottom). (B) Individual pie charts for CD4+ T cells from NT and ST at T0, T1, and T2 showing multifunctional responses of IFNg, TNFA, Granzyme B, and perforin; figure arcs surrounding pie chart display expression of each cytokine across pie chart. (C) Direct comparison of multifunctional response based on telomere length (*p<0.05). (D) Heatmap showing changes in multifunctional response over time, T1 and T2 are compared to T0 (*p<0.05).