Table 1.
Cohort Study (N = 106) | Sub-set analysis (N = 24) | |||
---|---|---|---|---|
|
||||
Normal Telomere (N = 49) | Short Telomere (N = 57) | Normal Telomere (N = 11) | Short Telomere (N = 13) | |
|
||||
Male (%) | 38 (78%) | 44 (77%) | 9 (82%) | 8 (62%) |
Age (Median, Range) | 64 (44–74) | 61 (43–76) | 62 (55 – 70) | 55(45–69) |
Double lung | 43 (88%) | 44 (77%) | 10 (91%) | 11 (85%) |
Induction: | ||||
basiliximab | 25 (51%) | 29 (51%) | 8 (73%) | 10 (77%) |
alemtuzumab | 24 (49%) | 28 (49%) | 3 (27%) | 3 (23%) |
Telomere length* | ||||
<1 | 0 | 19 | 0 | 9 |
1–10 | 0 | 38 | 0 | 4 |
10–50 | 42 | 0 | 8 | 0 |
>50 | 7 | 0 | 3 | 0 |
Genetic Testing | 26 (53%) | 40 (70%) | 5 (45%) | 8 (62%) |
Variant Identified | 5(19%) | 21(53%) | 2 (40%) | 5 (63%) |
CMV Donor + | 32 (65%) | 43 (75%) | 7 (64%) | 9 (69%) |
Lymphocyte telomere length reported as age-adjusted percentile