Table 6. Allergic reactions within 14 days of applying the oils to dogs’ skin.

Parameters		16% Clove oil	16% Zanthoxylum limonella oil	Positive control (Bayticol)	Negative control (essential oil solvent-ethyl alcohol 95 %)
Allergic reactions occurred within 15 min of applying the oils to the dogs’ skin
	- Abnormalities (scratching, itching, rubbing the body against furniture or objects)	29.41%	41.18%	46.67%	16.67%
	- Abnormalities (red bumps)	0.00%	0.00%	0.00%	0.00%
	- Abnormalities (dermatitis)	0.00%	0.00%	0.00%	0.00%
	- No abnormalities	70.59%	58.82%	53.33%	83.33%
Allergic reactions occurred 2 days after applying the oils to the dogs’ skin
	- Abnormalities (scratching, itching, rubbing the body against furniture or objects)	5.88%	17.65%	20.00%	0.00%
	- Abnormalities (red bumps)	0.00%	0.00%	0.00%	5.56%
	- Abnormalities (dermatitis)	0.00%	0.00%	0.00%	5.56%
	- No abnormalities	94.12%	82.35%	80.00%	88.89%
Allergic reactions occurred 3 days after applying the oils to the dogs’ skin
	- Abnormalities (scratching, itching, rubbing the body against furniture or objects)	5.88%	17.65%	13.33%	5.56%
	- Abnormalities (red bumps)	0.00%	0.00%	0.00%	0.00%
	- Abnormalities (dermatitis)	0.00%	0.00%	0.00%	5.56%
	- No abnormalities	94.12%	82.35%	86.67%	88.89%
Allergic reactions occurred 7 days after applying the oils to the dogs’ skin
	- Abnormalities (scratching, itching, rubbing the body against furniture or objects)	5.88%	17.65%	13.33%	11.11%
	- Abnormalities (red bumps)	0.00%	0.00%	0.00%	0.00%
	- Abnormalities (dermatitis)	0.00%	0.00%	0.00%	0.00%
	- No abnormalities	94.12%	82.35%	86.67%	88.89%
Allergic reactions occurred 14 days after applying the oils to the dogs’ skin
	- Abnormalities (scratching, itching, rubbing the body against furniture or objects)	0.00%	6.25%	26.67%	11.11%
	- Abnormalities (red bumps)	0.00%	0.00%	0.00%	5.56%
	- Abnormalities (dermatitis)	0.00%	0.00%	0.00%	0.00%
	- No abnormalities	100.00%	93.75%	73.33%	83.33%